Phenytoin and anemia
WebMay 1, 1983 · A 53-yr-old man sequentially developed aplastic anemia from phenytoin and Carbamazepins. Both compounds undergo metabolism to potentially toxic arene oxide intermediates. We tested the hypothesis that the patient's adverse reactions were due to a defect in detoxification of such metabolites by challenging his peripheral lymphocytes … WebSep 20, 2024 · There are so many different types of anemia that it can sometimes feel overwhelming. That’s why I’m breaking down the key types in this article. ... Medications can cause vitamin deficiencies, including antibiotics, antacids, metformin (antidiabetic) and phenytoin (antiseizure). Tapeworm infections can lead to lower vitamin levels. Some ...
Phenytoin and anemia
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Webpatients were taking phenytoin sodium only, four patients were taking phenytoin sodium and phenobarbitone, and two patients were taking primidone in addition to phenytoin sodium and phenobarbitone (Chalmers and Boheimer, 1954; Berlyne et al., I955). It is unlikely that the anticonvulsant drugs were responsible for the anaemia in two of these ... WebAbsence or decreased number of hematopoietic precursor cells → pancytopenia ( anemia, thrombocytopenia, neutropenia) Causes: Drug-induced ( chloramphenicol, carbamazepine, valproic acid, phenytoin) Viral infection ( parvovirus B19, HIV, hepatitis ), especially in patients with sickle cell disease or immunocompromise. Autoimmune.
WebJun 15, 2010 · Anemia after toxin ingestion or viral illness, usually in children 6 months to 3 years of age. Normocytic anemia, initially with reticulocyte count of 0; anemia resolves … WebPhenytoin also can cause anemia. Because it interferes with vitamin D metabolism, phenytoin can cause weakening of the bones (osteomalacia). Other important side …
WebA 53-yr-old man sequentially developed aplastic anemia from phenytoin and carbamazepine. Both compounds undergo metabolism to potentially toxic arene oxide intermediates. We … WebFeb 9, 2024 · Summary. Commonly reported side effects of phenytoin include: congenital anomalies. Other side effects include: hepatic necrosis, ataxia, confusion, constipation, depression, dizziness, drowsiness, fatigue, hypertrichosis, mental status changes, …
Webuse of AEDs was significantly associated with aplastic anemia (adjusted odds ratio (OR), 9.5; 95% confidence interval (CI), 3.0–39.7). The most frequently used AEDs were carbamazepine (CBZ), valproic acid (VPA), and phenytoin. The 16 exposed cases were heterogeneous with respect to patient and exposure
WebThere are 12 disease interactions with phenytoin. Blood dyscrasias Liver disease Porphyria Renal dysfunction Cardiotoxicity Suicidal tendency Arrhythmias Hyperglycemia … times of india customer care email idWebf Phenytoin is a PROBABLE TERATOGEN in humans. f Phenytoin has caused CANCER in the offspring of animals exposed during pregnancy. Other Effects f Phenytoin may cause a skin allergy. If allergy develops, very low future exposure can cause itching and a skin rash. f High or repeated exposures to Phenytoin can cause anemia. parenting collectiveWebPhenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. parenting coaching programsWebFeb 1, 2009 · Pernicious anemia is most commonly caused by auto-immune atrophic gastritis, in which autoantibodies are directed against parietal cells and intrinsic factor. … parenting code of ethicsWebGydell has suggested that a subclinical nutritional deficiency may be a predisposing factor [77]. The present report describes two cases of megaloblastic anemia associated with the use of Dilantin and barbiturate derivatives. Detailed nutritional studies revealed evidence of multiple deficiencies in both patients. parenting coffee table bookWebPhenytoin Probenecid (Benemid) Procainamide (Pronestyl) Pyrimethamine (Daraprim) Quinine Streptomycin Sulfa-containing drugs § (sulfacetamide, sulfadiazine, sulfamethoxazole [Gantanol], trimethoprim-sulfamethoxazole, sulfamethoxypyridazine [Kynex], sulfanilamide, sulfisoxazole [Gantrisin]) Tiaprofenic acid Trimethoprim parenting coach sydneyWebPhenytoin and anemia Common Questions and Answers about Phenytoin and anemia dilantin The antiepileptic drugs need to be checked for a dosage modulation, assessment … timesofindia daily horoscope