Hens as the model for ovarian cancer
Web29 jul. 2011 · The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors Yi Yu, Seby L Edassery, Animesh Barua, Jacques S Abramowicz, Janice M Bahr, Ingegerd Hellstrom & Judith L Luborsky Journal of Ovarian Research 4, Article number: 12 ( 2011 ) Cite this article … Web18 jan. 2024 · In order to track micro-metastatic disease, the group began by engineering the ID8 murine ovarian cancer cell line to express an enhanced luciferase construct, …
Hens as the model for ovarian cancer
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Web11 aug. 2015 · Johnson PA, Giles JR. The hen as a model of ovarian cancer. Nat Rev Cancer. 2013; 13:432–436. doi: 10.1038/nrc3535. ... Gangi LM, et al. Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: functional similarity to the human disease and identification of prospective tumoral markers and targets. J ... WebA transvaginal ultrasound (TVUS) imaging method for imaging of hen ovarian tumors has been developed. Hens can be monitored prospectively by using serum markers, together …
Web1 sep. 2004 · Characterization of the Hen as a Model for Human Ovarian Cancer Authors: Patricia A Johnson Abstract Investigation of basic factors involved in malignant … Web16 mei 2013 · Laying hen has been known as a robust model of spontaneous ovarian cancer in human due to the expression of some molecular markers, proin ammatory …
Web21 nov. 2012 · Stammer K, Edassery SL, Barua A, Bitterman P, Bahr JM, et al. (2008) Selenium-Binding Protein 1 expression in ovaries and ovarian tumors in the laying hen, a spontaneous model of human ovarian cancer. Gynecol Oncol 109: 115–121. View Article Google Scholar 10. Web16 mei 2013 · The domestic laying hen is the only non-human animal that spontaneously develops ovarian cancer with a high prevalence. Hens ovulate prolifically, and this has made the hen intuitively appealing as a model of this disease in light of epidemiological evidence that ovulation rate is highly correlated with the risk of human ovarian cancer.
Web27 jul. 2024 · Therefore, hens have the potential to be a biologically and clinically relevant model of spontaneous OVCA to examine the etiology, pathophysiology, and progression of OVCA and to develop diagnostics and therapeutic interventions.
WebUp to 30 to 35% of domestic hens develop ovarian cancer by the time they are 2.5 years old (Fredrickson,1987). As a result of this frequency, hens were used as an animal model for ovarian cancer in woman. The … flannel shirt with pocketWebPersonal research interests: further optimization and validation of the laying hen spontaneous model of ovarian cancer for preclinical studies. … can sheep find their way homeWeb1 apr. 2012 · The laying hen is also a model of human ovarian cancer, because ovarian tumors with histological characteristics and stages similar to those in women occur … can sheep get up if they fall on their backWebInvestigation of basic factors involved in malignant transformation of the ovary has been hampered by the lack of an appropriate animal model. Most animals, with the exception … can sheep get lyme diseaseWebPersonal research interests: further optimization and validation of the laying hen spontaneous model of ovarian cancer for preclinical studies. … flannel shirt with rabbitsWeb18 nov. 2010 · The hen is the only spontaneous animal model of ovarian cancer and can therefore aid in the identification and testing of early detection strategies and therapeutics. Hens have a high incidence of ovarian cancer and, similar to women, this incidence increases with age [ 3 ]. can sheep fur be straightWeb27 jul. 2024 · Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In most cases it is detected at late stages as the symptoms are non … can sheep eat red clover